Prion Strain Discrimination Based on Rapid In Vivo Amplification and Analysis by the Cell Panel Assay

Prion strain identification has been hitherto achieved using time-consuming incubation time determinations in one or more mouse lines and elaborate neuropathological assessment. In the present work, we make a detailed study of the properties of PrP-overproducing Tga20 mice. We show that in these mic...

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Main Authors: Karapetyan, Yervand Eduard, Saá, Paula, Mahal, Sukhvir Paul, Sferrazza, Gian Franco, Sherman, Alexandra, Salès, Nicole, Weissmann, Charles, Lasmézas, Corinne Ida
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2009
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2684634/
https://ncbi.nlm.nih.gov/pubmed/19478942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005730
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