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Prion strain discrimination in cell culture: The cell panel assay

Prions are thought to consist mainly or entirely of misfolded PrP, a constitutively expressed host protein. Prions associated with the same PrP sequence may occur in the form of different strains; the strain phenotype is believed to be encoded by the conformation of the PrP. Some cell lines can be p...

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Autors principals: Mahal, Sukhvir P., Baker, Christopher A., Demczyk, Cheryl A., Smith, Emery W., Julius, Christian, Weissmann, Charles
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409240/
https://ncbi.nlm.nih.gov/pubmed/18077360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0710054104
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