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Highly neurotoxic monomeric α-helical prion protein

Prion diseases are infectious and belong to the group of protein misfolding neurodegenerative diseases. In these diseases, neuronal dysfunction and death are caused by the neuronal toxicity of a particular misfolded form of their cognate protein. The ability to specifically target the toxic protein...

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Detalhes bibliográficos
Main Authors: Zhou, Minghai, Ottenberg, Gregory, Sferrazza, Gian Franco, Lasmézas, Corinne Ida
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3286986/
https://ncbi.nlm.nih.gov/pubmed/22323583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1118090109
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