Highly infectious prions are not directly neurotoxic

Prions are infectious agents which cause rapidly lethal neurodegenerative diseases in humans and animals following long, clinically silent incubation periods. They are composed of multichain assemblies of misfolded cellular prion protein. While it has long been assumed that prions are themselves neu...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Benilova, Iryna, Reilly, Madeleine, Terry, Cassandra, Wenborn, Adam, Schmidt, Christian, Marinho, Aline T., Risse, Emmanuel, Al-Doujaily, Huda, Wiggins De Oliveira, Michael, Sandberg, Malin K., Wadsworth, Jonathan D. F., Jat, Parmjit S., Collinge, John
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2020
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7525444/
https://ncbi.nlm.nih.gov/pubmed/32900920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2007406117
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