Activation of the NF-κB pathway by adeno-associated virus (AAV) vectors and its implications in immune response and gene therapy

Por Jayandharan, Giridhara R., Aslanidi, George, Martino, Ashley T., Jahn, Stephan C., Perrin, George Q., Herzog, Roland W., Srivastava, Arun
Publicado em 2011

Analysis of steroid hormone effects on xenografted human NF1 tumor Schwann cells

Por Li, Hua, Zhang, Xuelian, Fishbein, Lauren, Kweh, Frederick, Thompson, Martha Campbell, Perrin, George Q, Muir, David, Wallace, Margaret
Publicado em 2010

Prevention and Reversal of Antibody Responses Against Factor IX in Gene Therapy for Hemophilia B

Por Nayak, Sushrusha, Sarkar, Debalina, Perrin, George Q., Moghimi, Babak, Hoffman, Brad E., Zhou, Shangzhen, Byrne, Barry J., Herzog, Roland W.
Publicado em 2011

Regulatory T cells and TLR9 Activation Shape Antibody Formation to a Secreted Transgene Product in AAV Muscle Gene Transfer

Por Herzog, Roland W., Cooper, Mario, Perrin, George Q., Biswas M, Moanaro, Martino, Ashley T., Morel, Laurence, Terhorst, Cox, Hoffman, Brad E.
Publicado no Cell Immunol (2017)

Dynamics of antigen presentation to transgene product-specific CD4(+) T cells and of Treg induction upon hepatic AAV gene transfer

Por Perrin, George Q, Zolotukhin, Irene, Sherman, Alexandra, Biswas, Moanaro, de Jong, Ype P, Terhorst, Cox, Davidoff, Andrew M, Herzog, Roland W
Publicado no Mol Ther Methods Clin Dev (2016)

Effective gene therapy for haemophilic mice with pathogenic factor IX antibodies

Por Markusic, David M, Hoffman, Brad E, Perrin, George Q, Nayak, Sushrusha, Wang, Xiaomei, LoDuca, Paul A, High, Katherine A, Herzog, Roland W
Publicado em 2013

Ex vivo expanded autologous polyclonal regulatory T cells suppress inhibitor formation in hemophilia

Por Sarkar, Debalina, Biswas, Moanaro, Liao, Gongxian, Seay, Howard R, Perrin, George Q, Markusic, David M, Hoffman, Brad E, Brusko, Todd M, Terhorst, Cox, Herzog, Roland W
Publicado em 2014

Oral Tolerance Induction in Hemophilia B Dogs Fed with Transplastomic Lettuce

Por Herzog, Roland W., Nichols, Timothy C., Su, Jin, Zhang, Bei, Sherman, Alexandra, Merricks, Elizabeth P., Raymer, Robin, Perrin, George Q., Häger, Mattias, Wiinberg, Bo, Daniell, Henry
Publicado no Mol Ther (2017)

Plasmacytoid and conventional dendritic cells cooperate in crosspriming AAV capsid-specific CD8(+) T cells

Por Rogers, Geoffrey L., Shirley, Jamie L., Zolotukhin, Irene, Kumar, Sandeep R. P., Sherman, Alexandra, Perrin, George Q., Hoffman, Brad E., Srivastava, Arun, Basner-Tschakarjan, Etiena, Wallet, Mark A., Terhorst, Cox, Biswas, Moanaro, Herzog, Roland W.
Publicado no Blood (2017)