CTIM-04. UPDATES FOR A PHASE 2 OPEN-LABELED STUDY OF PEMBROLIZUMAB PLUS TTFIELDS PLUS MAINTENANCE TEMOZOLOMIDE IN PATIENTS WITH NEWLY DIAGNOSED GLIOBLASTOMA (2-THE-TOP)

INTRODUCTION: Tumor-treating fields (TTFields) are a new standard anti-mitotic treatment for newly diagnosed glioblastoma (ndGBM). Emerging data indicate that TTFields also stimulate innate immunity, leading to adaptive immunity. We hypothesize that immune checkpoint inhibitors synergize with TTFiel...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Ghiaseddin, Ashley, Warren, Sonisha, Allen, Annie, Sampson, Deborah, Chen, Dongjiang, Sherman, Alexandra, Greene, Valerie, Rahman, Maryam, Tran, David
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Clinical Trials: Immunologic
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7650429/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.138
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