Depletion of K-Ras promotes proteasome degradation of survivin

Por Tecleab, Awet, Sebti, Saïd M.
Publicado em 2013

Measurement of protein farnesylation and geranylgeranylation in vitro, in cultured cells and in biopsies, and the effects of prenyl transferase inhibitors

Por Berndt, Norbert, Sebti, Saïd M
Publicado em 2011

Ral GTPase Down-regulation Stabilizes and Reactivates p53 to Inhibit Malignant Transformation

Por Tecleab, Awet, Zhang, Xiaolei, Sebti, Said M.
Publicado no J Biol Chem (2014)

Targeting protein prenylation for cancer therapy

Por Berndt, Norbert, Hamilton, Andrew D., Sebti, Saïd M.
Publicado em 2011

TNFα-mediated proliferation of vascular smooth muscle cells involves Raf-1-mediated inactivation of Rb and transcription of E2F1-regulated genes

Por Davis, Rebecca, Pillai, Smitha, Lawrence, Nicholas, Sebti, Said, Chellappan, Srikumar P
Publicado em 2012

Akt2 and acid ceramidase cooperate to induce cell invasion and resistance to apoptosis

Por Berndt, Norbert, Patel, Ronil, Yang, Hua, Balasis, Maria E., Sebti, Saïd M.
Publicado em 2013

Identification of novel ROCK inhibitors with anti-migratory and anti-invasive activities

Por Patel, Ronil A., Liu, Yan, Wang, Binglin, Li, Rongshi, Sebti, Saïd M.
Publicado em 2013

p21(WAF1/CIP1) Is Upregulated by the Geranylgeranyltransferase I Inhibitor GGTI-298 through a Transforming Growth Factor β- and Sp1-Responsive Element: Involvement of the Small G...

Por Adnane, Jalila, Bizouarn, Francisco A., Qian, Yimin, Hamilton, Andrew D., Sebti, Saïd M.
Publicado em 1998

Akt Mediates Ras Downregulation of RhoB, a Suppressor of Transformation, Invasion, and Metastasis

Por Jiang, Kun, Sun, Jiazhi, Cheng, Jin, Djeu, Julie Y., Wei, Sheng, Sebti, Saïd
Publicado em 2004

Identification of novel inhibitors that disrupt STAT3/DNA interaction from γ-AApeptide OBOC combinatorial library

Por Teng, Peng, Zhang, Xiaolei, Wu, Haifan, Qiao, Qiao, Sebti, Said M., Cai, Jianfeng
Publicado em 2014

Targeting Protein Tyrosine Phosphatases for Anticancer Drug Discovery

Por Scott, Latanya. M., Lawrence, Harshani. R., Sebti, Saïd. M., Lawrence, Nicholas. J., Wu, Jie.
Publicado em 2010

Poly[(μ(3)-hydrogenphosphato)(4H-1,2,4-triazole-κN (1))zinc]

Por Aitenneite, Hafid, El Bouari, Abdeslam, Sebti, Said, Saadi, Mohamed, El Ammari, Lahcen, Adil, Karim
Publicado em 2012

Discovery of PI-1840, a Novel Noncovalent and Rapidly Reversible Proteasome Inhibitor with Anti-tumor Activity

Por Kazi, Aslamuzzaman, Ozcan, Sevil, Tecleab, Awet, Sun, Ying, Lawrence, Harshani R., Sebti, Saïd M.
Publicado em 2014

Regulation of dendritic cell differentiation and antitumor immune response in cancer by pharmacological selective inhibition of the Jak2/STAT3 pathway

Por Nefedova, Yulia, Nagaraj, Srinivas, Rosenbauer, Amsler, Muro-Cacho, Carlos, Sebti, Said M., Gabrilovich, Dmitry I.
Publicado em 2005

Vitamin E δ-Tocotrienol Augments the Anti-tumor Activity of Gemcitabine and Suppresses Constitutive NF-κB Activation in Pancreatic Cancer

Por Husain, Kazim, Francois, Rony A., Yamauchi, Teruo, Perez, Marta, Sebti, Said M., Malafa, Mokenge P.
Publicado em 2011

δ-Tocotrienol, a natural form of vitamin E, inhibits pancreatic cancer stem-like cells and prevents pancreatic cancer metastasis

Por Husain, Kazim, Centeno, Barbara A, Coppola, Domenico, Trevino, Jose, Sebti, Said M, Malafa, Mokenge P
Publicado no Oncotarget (2017)

Structure-based Design of High Affinity Peptides Inhibiting the Interaction of p53 with MDM2 and MDMX

Por Phan, Jason, Li, Zhenyu, Kasprzak, Agnieszka, Li, Baozong, Sebti, Said, Guida, Wayne, Schönbrunn, Ernst, Chen, Jiandong
Publicado em 2010

Rb-Raf-1 interaction disruptor RRD-251 induces apoptosis in metastatic melanoma cells and synergizes with dacarbazine

Por Singh, Sandeep, Davis, Rebecca, Alamanda, Vignesh, Pireddu, Roberta, Pernazza, Daniel, Sebti, Said, Lawrence, Nicholas, Chellappan, Srikumar
Publicado em 2010

Regulation of Matrix Metalloproteinase Genes by E2F transcription factors: Rb-Raf-1 interaction as a novel target for metastatic disease

Por Johnson, Jackie L., Pillai, Smitha, Pernazza, Danielle, Sebti, Said M., Lawrence, Nicholas J., Chellappan, Srikumar P.
Publicado em 2011

Activation of dendritic cells via inhibition of Jak2/STAT3 signaling

Por Nefedova, Yulia, Cheng, Pingyan, Gilkes, Daniele, Blaskovich, Michelle, Beg, Amer A., Sebti, Said M., Gabrilovich, Dmitry I.
Publicado em 2005