Activation of dendritic cells via inhibition of Jak2/STAT3 signaling

Signaling via Jak2/STAT3 is critically important for normal dendritic cells (DC) differentiation. In addition, we have previously demonstrated that hyper-activation of the Jak2/STAT3 pathway induced by tumor-derived factors (TDF) may be responsible for abnormal DC differentiation in cancer. Here, us...

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Main Authors: Nefedova, Yulia, Cheng, Pingyan, Gilkes, Daniele, Blaskovich, Michelle, Beg, Amer A., Sebti, Said M., Gabrilovich, Dmitry I.
Formato: Artigo
Idioma:Inglês
Publicado: 2005
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1351251/
https://ncbi.nlm.nih.gov/pubmed/16177074
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