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Akt2 and acid ceramidase cooperate to induce cell invasion and resistance to apoptosis
Both Akt 2 and acid ceramidase (ASAH1) are found aberrantly overexpressed in cancer cells, but whether these two enzymes cooperate to induce malignant transformation is not known. We found that in immortalized, non-transformed cells, ectopic co-expression of Akt2 and ASAH1 is significantly more effe...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3737305/ https://ncbi.nlm.nih.gov/pubmed/23777806 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.25043 |
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