Regulation of apoptosis-inducing factor-mediated, cisplatin-induced apoptosis by Akt

Cisplatin is a first-line chemotherapeutic for ovarian cancer, although chemoresistance limits treatment success. Apoptosis, an important determinant of cisplatin sensitivity, occurs via caspase-dependent and -independent mechanisms. Activation of the protein kinase Akt, commonly observed in ovarian...

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Detaylı Bibliyografya
Asıl Yazarlar: Yang, X, Fraser, M, Abedini, M R, Bai, T, Tsang, B K
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2008
Konular:
Translational Therapeutics
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2259169/
https://ncbi.nlm.nih.gov/pubmed/18283299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604223
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