Lessons from Polyoma Middle T Antigen on Signaling and Transformation: A DNA Tumor Virus Contribution to the War on Cancer

Por Schaffhausen, Brian S., Roberts, Thomas M.
Publicado em 2008

Lessons in Signaling and Tumorigenesis from Polyomavirus Middle T Antigen

Por Fluck, Michele M., Schaffhausen, Brian S.
Publicado em 2009

A Transformation-Defective Polyomavirus Middle T Antigen with a Novel Defect in PI3 Kinase Signaling

Por Denis, Deborah, Rouleau, Cecile, Schaffhausen, Brian S.
Publicado no J Virol (2017)

J Domain-Independent Regulation of the Rb Family by Polyomavirus Large T Antigen

Por Sheng, Qing, Love, Tara M., Schaffhausen, Brian
Publicado em 2000

Tumor antigen(s) in cells productively infected by wild-type polyoma virus and mutant NG-18

Por Schaffhausen, Brian S., Silver, Jonathan E., Benjamin, Thomas L.
Publicado em 1978

Signaling from Polyomavirus Middle T and Small T Defines Different Roles for Protein Phosphatase 2A

Por Mullane, Karen P., Ratnofsky, Mara, Culleré, Xavier, Schaffhausen, Brian
Publicado em 1998

Viral Interference with DNA Repair by Targeting of the Single-Stranded DNA Binding Protein RPA

Por Banerjee, Pubali, deJesus, Rowena, Gjoerup, Ole, Schaffhausen, Brian S.
Publicado em 2013

The p110α Isoform of Phosphatidylinositol 3-Kinase Is Essential for Polyomavirus Middle T Antigen-Mediated Transformation

Por Utermark, Tamara, Schaffhausen, Brian S., Roberts, Thomas M., Zhao, Jean J.
Publicado em 2007

PDK1 mediates growth factor-induced Ral-GEF activation by a kinase-independent mechanism

Por Tian, Xuejun, Rusanescu, Gabriel, Hou, Weimin, Schaffhausen, Brian, Feig, Larry A.
Publicado em 2002

Genetic Analysis of the Polyomavirus DnaJ Domain

Por Whalen, Kerry A., de Jesus, Rowena, Kean, Jennifer A., Schaffhausen, Brian S.
Publicado em 2005

Polyomavirus Middle T Antigen Induces the Transcription of Osteopontin, a Gene Important for the Migration of Transformed Cells

Por Whalen, Kerry A., Weber, Georg F., Benjamin, Thomas L., Schaffhausen, Brian S.
Publicado em 2008

Cellular Transformation by Simian Virus 40 and Murine Polyoma Virus T antigens

Por Cheng, Jingwei, DeCaprio, James A., Fluck, Michele M., Schaffhausen, Brian S.
Publicado em 2009

Protein Phosphatase 2A Isoforms Utilizing Aβ Scaffolds Regulate Differentiation through Control of Akt Protein

Por Hwang, Justin H., Jiang, Tao, Kulkarni, Shreya, Faure, Nathalie, Schaffhausen, Brian S.
Publicado em 2013

A new class of mutations reveals a novel function for the original phosphatidylinositol 3-kinase binding site

Por Hong, Y. Kate, Mikami, Aki, Schaffhausen, Brian, Jun, Toni, Roberts, Thomas M.
Publicado em 2003

Protein phosphatase 2A regulates life and death decisions via Akt in a context-dependent manner

Por Andrabi, Shaida, Gjoerup, Ole V., Kean, Jennifer A., Roberts, Thomas M., Schaffhausen, Brian
Publicado em 2007

Comparisons between Murine Polyomavirus and Simian Virus 40 Show Significant Differences in Small T Antigen Function

Por Andrabi, Shaida, Hwang, Justin H., Choe, Jennifer Kean, Roberts, Thomas M., Schaffhausen, Brian S.
Publicado em 2011

The Phosphatidylinositol 3-Kinase (PI3K) Isoform Dependence of Tumor Formation Is Determined by the Genetic Mode of PI3K Pathway Activation Rather than by Tissue Type

Por Utermark, Tamara, Schmit, Fabienne, Lee, Sang Hyun, Gao, Xueliang, Schaffhausen, Brian S., Roberts, Thomas M.
Publicado em 2014

Activation of CREB/ATF Sites by Polyomavirus Large T Antigen

Por Love, Tara M., de Jesus, Rowena, Kean, Jennifer A., Sheng, Qing, Leger, Andrew, Schaffhausen, Brian
Publicado em 2005

Essential role of PDK1 in regulating endothelial cell migration

Por Primo, Luca, di Blasio, Laura, Roca, Cristina, Droetto, Sara, Piva, Roberto, Schaffhausen, Brian, Bussolino, Federico
Publicado em 2007

Lentivirus-Mediated Oncogene Introduction into Mammary Cells In Vivo Induces Tumors

Por Siwko, Stefan K, Bu, Wen, Gutierrez, Carolina, Lewis, Brian, Jechlinger, Martin, Schaffhausen, Brian, Li, Yi
Publicado em 2008