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Cellular Transformation by Simian Virus 40 and Murine Polyoma Virus T antigens

Simian Virus 40 (SV40) and Mouse Polyoma Virus (PY) are small DNA tumor viruses that have been used extensively to study cellular transformation. The SV40 early region encodes three tumor antigens, Large T (LT), small T (ST) and 17KT that contribute to cellular transformation. While PY also encodes...

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Bibliographic Details
Main Authors: Cheng, Jingwei, DeCaprio, James A., Fluck, Michele M., Schaffhausen, Brian S.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2694755/
https://ncbi.nlm.nih.gov/pubmed/19505649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2009.03.002
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