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Simian Virus 40 Large T Antigen's Association with the CUL7 SCF Complex Contributes to Cellular Transformation

Simian virus 40 large T antigen (T Ag) is capable of immortalizing and transforming rodent cells. The transforming activity of T Ag is due in large part to perturbation of the tumor suppressor proteins p53 and the retinoblastoma (pRB) family members. Inactivation of these tumor suppressors may not b...

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Hlavní autoři: Kasper, Jocelyn S., Kuwabara, Hiroshi, Arai, Takehiro, Ali, Syed Hamid, DeCaprio, James A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1212609/
https://ncbi.nlm.nih.gov/pubmed/16140746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.18.11685-11692.2005
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