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PDK1 mediates growth factor-induced Ral-GEF activation by a kinase-independent mechanism
Ras proteins transduce extracellular signals to intracellular signaling pathways by binding to and promoting the activation of at least three classes of downstream signaling molecules: Raf kinases, phosphoinositide-3-kinase (PI3-K) and Ral guanine nucleotide exchange factors (Ral-GEFs). Previous wor...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2002
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125928/ https://ncbi.nlm.nih.gov/pubmed/11889038 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.6.1327 |
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