Activation of CREB/ATF Sites by Polyomavirus Large T Antigen

Polyomavirus large T antigen (LT) has a direct role in viral replication and a profound effect on cell phenotype. It promotes cell cycle progression, immortalizes primary cells, blocks differentiation, and causes apoptosis. While much of large T function is related to its effects on tumor suppressor...

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Main Authors: Love, Tara M., de Jesus, Rowena, Kean, Jennifer A., Sheng, Qing, Leger, Andrew, Schaffhausen, Brian
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2005
Ábhair:
Genome Replication and Regulation of Viral Gene Expression
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1061560/
https://ncbi.nlm.nih.gov/pubmed/15767419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.7.4180-4190.2005
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