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J Domain-Independent Regulation of the Rb Family by Polyomavirus Large T Antigen

The ability of polyomavirus large T antigen (LT) to promote cell cycling, to immortalize primary cells, and to block differentiation has been linked to its effects on tumor suppressors of the retinoblastoma susceptibility (Rb) gene family. Our previous studies have shown that LT requires an intact N...

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Detalhes bibliográficos
Main Authors: Sheng, Qing, Love, Tara M., Schaffhausen, Brian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC110883/
https://ncbi.nlm.nih.gov/pubmed/10799605
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