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The p110α Isoform of Phosphatidylinositol 3-Kinase Is Essential for Polyomavirus Middle T Antigen-Mediated Transformation

Middle T antigen (MT) of polyomavirus is known to play an important role in virus-mediated cellular transformation. While MT has been extensively examined in spontaneously immortalized rodent fibroblasts, its interactions with cells of other types and species are less well understood. We have undert...

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Main Authors: Utermark, Tamara, Schaffhausen, Brian S., Roberts, Thomas M., Zhao, Jean J.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2007
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1933267/
https://ncbi.nlm.nih.gov/pubmed/17442716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00115-07
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