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Lessons from Polyoma Middle T Antigen on Signaling and Transformation: A DNA Tumor Virus Contribution to the War on Cancer

Middle T antigen (MT) is the principal oncogene of murine polyomavirus. Its study has led to the discovery of the roles tyrosine kinase and phosphoinositide 3-kinase (PI3K) signaling in mammalian growth control and transformation. MT is necessary for viral transformation in tissue culture cells and...

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書誌詳細
主要な著者: Schaffhausen, Brian S., Roberts, Thomas M.
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676342/
https://ncbi.nlm.nih.gov/pubmed/19022468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2008.09.042
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