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Lessons from Polyoma Middle T Antigen on Signaling and Transformation: A DNA Tumor Virus Contribution to the War on Cancer
Middle T antigen (MT) is the principal oncogene of murine polyomavirus. Its study has led to the discovery of the roles tyrosine kinase and phosphoinositide 3-kinase (PI3K) signaling in mammalian growth control and transformation. MT is necessary for viral transformation in tissue culture cells and...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2676342/ https://ncbi.nlm.nih.gov/pubmed/19022468 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2008.09.042 |
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