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Genetic Analysis of the Polyomavirus DnaJ Domain

Polyomavirus T antigens share a common N-terminal sequence that comprises a DnaJ domain. DnaJ domains activate DnaK molecular chaperones. The functions of J domains have primarily been tested by mutation of their conserved HPD residues. Here, we report detailed mutagenesis of the polyomavirus J doma...

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Bibliographic Details
Main Authors: Whalen, Kerry A., de Jesus, Rowena, Kean, Jennifer A., Schaffhausen, Brian S.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2005
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1181550/
https://ncbi.nlm.nih.gov/pubmed/16014958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.15.9982-9990.2005
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