The DnaJ domain of polyomavirus large T antigen is required to regulate Rb family tumor suppressor function.

Tumor suppressors of the retinoblastoma susceptibility gene family regulate cell growth and differentiation. Polyomavirus large T antigens (large T) bind Rb family members and block their function. Mutations of large T sequences conserved with the DnaJ family affect large T binding to a cellular Dna...

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Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Sheng, Q, Denis, D, Ratnofsky, M, Roberts, T M, DeCaprio, J A, Schaffhausen, B
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1997
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC230245/
https://ncbi.nlm.nih.gov/pubmed/9371601
Etiketler: Etiketle
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