The DnaJ domain of polyomavirus large T antigen is required to regulate Rb family tumor suppressor function.

Tumor suppressors of the retinoblastoma susceptibility gene family regulate cell growth and differentiation. Polyomavirus large T antigens (large T) bind Rb family members and block their function. Mutations of large T sequences conserved with the DnaJ family affect large T binding to a cellular Dna...

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Bibliografske podrobnosti
Main Authors: Sheng, Q, Denis, D, Ratnofsky, M, Roberts, T M, DeCaprio, J A, Schaffhausen, B
Format: Artigo
Jezik:Inglês
Izdano: 1997
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC230245/
https://ncbi.nlm.nih.gov/pubmed/9371601
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