The DnaJ domain of polyomavirus large T antigen is required to regulate Rb family tumor suppressor function.

Tumor suppressors of the retinoblastoma susceptibility gene family regulate cell growth and differentiation. Polyomavirus large T antigens (large T) bind Rb family members and block their function. Mutations of large T sequences conserved with the DnaJ family affect large T binding to a cellular Dna...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Sheng, Q, Denis, D, Ratnofsky, M, Roberts, T M, DeCaprio, J A, Schaffhausen, B
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230245/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9371601/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.12.9410-9416.1997
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