Chargement en cours...

Three Regions of the pRB Pocket Domain Affect Its Inactivation by Human Papillomavirus E7 Proteins

A critical event in papillomavirus transformation of human cells is the inactivation of pRB by the E7 protein. E7, like many other viral oncoproteins, possesses a well-characterized LXCXE peptide motif that interacts with the pocket domain of pRB. Disruption of the LXCXE-binding cleft on pRB renders...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Dick, Frederick A., Dyson, Nicholas J.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2002
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC136242/
https://ncbi.nlm.nih.gov/pubmed/12021356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.12.6224-6234.2002
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!