The DnaJ domain of polyomavirus large T antigen is required to regulate Rb family tumor suppressor function.
Tumor suppressors of the retinoblastoma susceptibility gene family regulate cell growth and differentiation. Polyomavirus large T antigens (large T) bind Rb family members and block their function. Mutations of large T sequences conserved with the DnaJ family affect large T binding to a cellular Dna...
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| 出版年: | J Virol |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology (ASM)
1997
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230245/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9371601/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.12.9410-9416.1997 |
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