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Polyomavirus Large T Antigen Binds the Transcriptional Coactivator Protein p300

Using coimmunoprecipitation and glutathione S-transferase pulldown experiments, we found that polyomavirus large T antigen binds to p300 in vivo and in vitro. The N-terminal region of the viral protein, including the pRB binding motif, was dispensable for this interaction, which involved several reg...

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Detalhes bibliográficos
Main Authors: Nemethova, Maria, Wintersberger, Erhard
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC104009/
https://ncbi.nlm.nih.gov/pubmed/9882390
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