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Polyomavirus Large T Antigen Binds the Transcriptional Coactivator Protein p300

Using coimmunoprecipitation and glutathione S-transferase pulldown experiments, we found that polyomavirus large T antigen binds to p300 in vivo and in vitro. The N-terminal region of the viral protein, including the pRB binding motif, was dispensable for this interaction, which involved several reg...

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Dettagli Bibliografici
Pubblicato in:J Virol
Autori principali: Nemethova, Maria, Wintersberger, Erhard
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1999
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104009/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9882390/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.2.1734-1739.1999
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