The DnaJ domain of polyomavirus large T antigen is required to regulate Rb family tumor suppressor function.

Tumor suppressors of the retinoblastoma susceptibility gene family regulate cell growth and differentiation. Polyomavirus large T antigens (large T) bind Rb family members and block their function. Mutations of large T sequences conserved with the DnaJ family affect large T binding to a cellular Dna...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Sheng, Q, Denis, D, Ratnofsky, M, Roberts, T M, DeCaprio, J A, Schaffhausen, B
Médium: Artigo
Jazyk:Inglês
Vydáno: 1997
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC230245/
https://ncbi.nlm.nih.gov/pubmed/9371601
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky