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Polyomavirus Middle T Antigen Induces the Transcription of Osteopontin, a Gene Important for the Migration of Transformed Cells

Middle T antigen (MT) is the principal oncoprotein of murine polyomavirus. Experiments on the acute immediate effects of MT expression on cellular RNA levels showed that expression of osteopontin (OPN) was strongly induced by MT expression. Osteopontin is a protein known to be associated with cancer...

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Autores principales: Whalen, Kerry A., Weber, Georg F., Benjamin, Thomas L., Schaffhausen, Brian S.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2346735/
https://ncbi.nlm.nih.gov/pubmed/18337582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02650-07
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