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Polyomavirus Middle T Antigen Induces the Transcription of Osteopontin, a Gene Important for the Migration of Transformed Cells

Middle T antigen (MT) is the principal oncoprotein of murine polyomavirus. Experiments on the acute immediate effects of MT expression on cellular RNA levels showed that expression of osteopontin (OPN) was strongly induced by MT expression. Osteopontin is a protein known to be associated with cancer...

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Bibliografski detalji
Glavni autori: Whalen, Kerry A., Weber, Georg F., Benjamin, Thomas L., Schaffhausen, Brian S.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2346735/
https://ncbi.nlm.nih.gov/pubmed/18337582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02650-07
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