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Polyomavirus Middle T Antigen Induces the Transcription of Osteopontin, a Gene Important for the Migration of Transformed Cells

Middle T antigen (MT) is the principal oncoprotein of murine polyomavirus. Experiments on the acute immediate effects of MT expression on cellular RNA levels showed that expression of osteopontin (OPN) was strongly induced by MT expression. Osteopontin is a protein known to be associated with cancer...

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Detaylı Bibliyografya
Asıl Yazarlar: Whalen, Kerry A., Weber, Georg F., Benjamin, Thomas L., Schaffhausen, Brian S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 2008
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2346735/
https://ncbi.nlm.nih.gov/pubmed/18337582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02650-07
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