Efficient CRISPR-Cas9-mediated generation of knock-in human pluripotent stem cells lacking undesired mutations at the targeted locus

Autor Merkle, Florian T., Neuhausser, Werner M., Santos, David, Valen, Eivind, Gagnon, James A., Maas, Kristi, Sandoe, Jackson, Schier, Alexander F., Eggan, Kevin
Vydáno v Cell Rep (2015)

Tobacco nicotine uptake permease (NUP1) affects alkaloid metabolism

Autor Hildreth, Sherry B., Gehman, Elizabeth A., Yang, Haibing, Lu, Rong-He, K C, Ritesh, Harich, Kim C., Yu, Shi, Lin, Jinshan, Sandoe, Jackson L., Okumoto, Sakiko, Murphy, Angus S., Jelesko, John G.
Vydáno 2011

The C9orf72-interacting protein Smcr8 is a negative regulator of autoimmunity and lysosomal exocytosis

Autor Zhang, Yingying, Burberry, Aaron, Wang, Jin-Yuan, Sandoe, Jackson, Ghosh, Sulagna, Udeshi, Namrata D., Svinkina, Tanya, Mordes, Daniel A., Mok, Joanie, Charlton, Maura, Li, Quan-Zhen, Carr, Steven A., Eggan, Kevin
Vydáno v Genes Dev (2018)

Reactive Astrocytes Promote ALS-like Degeneration and Intracellular Protein Aggregation in Human Motor Neurons by Disrupting Autophagy through TGF-β1

Autor Tripathi, Pratibha, Rodriguez-Muela, Natalia, Klim, Joseph R., de Boer, A. Sophie, Agrawal, Sahil, Sandoe, Jackson, Lopes, Claudia S., Ogliari, Karolyn Sassi, Williams, Luis A., Shear, Matthew, Rubin, Lee L., Eggan, Kevin, Zhou, Qiao
Vydáno v Stem Cell Reports (2017)

A Stem Cell-Based Screening Platform Identifies Compounds that Desensitize Motor Neurons to Endoplasmic Reticulum Stress

Autor Thams, Sebastian, Lowry, Emily Rhodes, Larraufie, Marie-Hélène, Spiller, Krista J., Li, Hai, Williams, Damian J., Hoang, Phuong, Jiang, Elise, Williams, Luis A., Sandoe, Jackson, Eggan, Kevin, Lieberam, Ivo, Kanning, Kevin C., Stockwell, Brent R., Henderson, Christopher E., Wichterle, Hynek
Vydáno v Mol Ther (2019)

Intrinsic Membrane Hyperexcitability of ALS Patient-Derived Motor Neurons

Autor Wainger, Brian J., Kiskinis, Evangelos, Mellin, Cassidy, Wiskow, Ole, Han, Steve S.W., Sandoe, Jackson, Perez, Numa P., Williams, Luis A., Lee, Seungkyu, Boulting, Gabriella, Berry, James D., Brown, Robert H., Cudkowicz, Merit E., Bean, Bruce P., Eggan, Kevin, Woolf, Clifford J.
Vydáno 2014

Pathways Disrupted in Human ALS Motor Neurons Identified Through Genetic Correction of Mutant SOD1

Autor Kiskinis, Evangelos, Sandoe, Jackson, Williams, Luis A., Boulting, Gabriella L., Moccia, Rob, Wainger, Brian J., Han, Steve, Peng, Theodore, Thams, Sebastian, Mikkilineni, Shravani, Mellin, Cassidy, Merkle, Florian T., Davis-Dusenbery, Brandi N., Ziller, Michael, Oakley, Derek, Ichida, Justin, Dicostanza, Stefania, Atwater, Nick, Maeder, Morgan L., Goodwin, Mathew J., Nemesh, James, Handsaker, Robert E., Paull, Daniel, Noggle, Scott, McCarroll, Steven A., Joung, J. Keith, Woolf, Clifford J., Brown, Robert H, Eggan, Kevin
Vydáno v Cell Stem Cell (2014)

Lipidomic Analysis of α-Synuclein Neurotoxicity Identifies Stearoyl CoA Desaturase as a Target for Parkinson Treatment

Autor Fanning, Saranna, Haque, Aftabul, Imberdis, Thibaut, Baru, Valeriya, Barrasa, M. Inmaculada, Nuber, Silke, Termine, Daniel, Ramalingam, Nagendran, Ho, Gary P.H., Noble, Tallie, Sandoe, Jackson, Lou, Yali, Landgraf, Dirk, Freyzon, Yelena, Newby, Gregory, Soldner, Frank, Terry-Kantor, Elizabeth, Kim, Tae-Eun, Hofbauer, Harry F., Becuwe, Michel, Jaenisch, Rudolf, Pincus, David, Clish, Clary B., Walther, Tobias C., Farese, Robert V., Srinivasan, Supriya, Welte, Michael A., Kohlwein, Sepp D., Dettmer, Ulf, Lindquist, Susan, Selkoe, Dennis
Vydáno v Mol Cell (2018)