Conversion of Mouse and Human Fibroblasts into Functional Spinal Motor Neurons

Por Son, Esther Y., Ichida, Justin K., Wainger, Brian J., Toma, Jeremy S., Rafuse, Victor F., Woolf, Clifford J., Eggan, Kevin
Publicado em 2011

A Small Molecule Screen in Stem Cell-derived Motor Neurons Identifies a Kinase Inhibitor as a Candidate Therapeutic for ALS

Por Yang, Yin M., Gupta, Shailesh K., Kim, Kevin J., Powers, Berit E., Cerqueira, Antonio, Wainger, Brian J., Ngo, Hien D., Rosowski, Kathryn A., Schein, Pamela A., Ackeifi, Courtney A., Arvanites, Anthony C., Davidow, Lance S., Woolf, Clifford J., Rubin, Lee L.
Publicado em 2013

Intrinsic Membrane Hyperexcitability of ALS Patient-Derived Motor Neurons

Por Wainger, Brian J., Kiskinis, Evangelos, Mellin, Cassidy, Wiskow, Ole, Han, Steve S.W., Sandoe, Jackson, Perez, Numa P., Williams, Luis A., Lee, Seungkyu, Boulting, Gabriella, Berry, James D., Brown, Robert H., Cudkowicz, Merit E., Bean, Bruce P., Eggan, Kevin, Woolf, Clifford J.
Publicado em 2014

Modeling pain in vitro using nociceptor neurons reprogrammed from fibroblasts

Por Wainger, Brian J., Buttermore, Elizabeth D., Oliveira, Julia T., Mellin, Cassidy, Lee, Seungkyu, Saber, Wardiya Afshar, Wang, Amy, Ichida, Justin K., Chiu, Isaac M., Barrett, Lee, Huebner, Eric A., Bilgin, Canan, Tsujimoto, Naomi, Brenneis, Christian, Kapur, Kush, Rubin, Lee L., Eggan, Kevin, Woolf, Clifford J.
Publicado no Nat Neurosci (2014)

A functionally characterized test set of human induced pluripotent stem cells

Por Boulting, Gabriella L., Kiskinis, Evangelos, Croft, Gist F., Amoroso, Mackenzie W., Oakley, Derek H., Wainger, Brian J., Williams, Damian J., Kahler, David J., Yamaki, Mariko, Davidow, Lance, Rodolfa, Christopher T., Dimos, John T., Mikkilineni, Shravani, MacDermott, Amy B., Woolf, Clifford J., Henderson, Christopher E., Wichterle, Hynek, Eggan, Kevin
Publicado em 2011

A three-dimensional human neural cell culture model of Alzheimer’s disease

Por Choi, Se Hoon, Kim, Young Hye, Hebisch, Matthias, Sliwinski, Christopher, Lee, Seungkyu, D’Avanzo, Carla, Chen, Jennifer, Hooli, Basavaraj, Asselin, Caroline, Muffat, Julien, Klee, Justin B., Zhang, Can, Wainger, Brian J., Peitz, Michael, Kovacs, Dora M., Woolf, Clifford J., Wagner, Steven L., Tanzi, Rudolph E., Kim, Doo Yeon
Publicado no Nature (2014)

The RNA kinase CLP1 links tRNA metabolism to progressive motor neuron loss

Por Hanada, Toshikatsu, Weitzer, Stefan, Mair, Barbara, Bernreuther, Christian, Wainger, Brian J., Ichida, Justin, Hanada, Reiko, Orthofer, Michael, Cronin, Shane J, Komnenovic, Vukislav, Minis, Adi, Sato, Fuminori, Mimata, Hiromitsu, Yoshimura, Akihiko, Tamir, Ido, Rainer, Johannes, Kofler, Reinhard, Yaron, Avraham, Eggan, Kevin C., Woolf, Clifford J., Glatzel, Markus, Herbst, Ruth, Martinez, Javier, Penninger, Josef M.
Publicado em 2013

Pathways Disrupted in Human ALS Motor Neurons Identified Through Genetic Correction of Mutant SOD1

Por Kiskinis, Evangelos, Sandoe, Jackson, Williams, Luis A., Boulting, Gabriella L., Moccia, Rob, Wainger, Brian J., Han, Steve, Peng, Theodore, Thams, Sebastian, Mikkilineni, Shravani, Mellin, Cassidy, Merkle, Florian T., Davis-Dusenbery, Brandi N., Ziller, Michael, Oakley, Derek, Ichida, Justin, Dicostanza, Stefania, Atwater, Nick, Maeder, Morgan L., Goodwin, Mathew J., Nemesh, James, Handsaker, Robert E., Paull, Daniel, Noggle, Scott, McCarroll, Steven A., Joung, J. Keith, Woolf, Clifford J., Brown, Robert H, Eggan, Kevin
Publicado no Cell Stem Cell (2014)