Probing disorders of the nervous system using reprogramming approaches

Por Ichida, Justin K, Kiskinis, Evangelos
Publicado no EMBO J (2015)

New approaches for direct conversion of patient fibroblasts into neural cells

Por Gopalakrishnan, Suhasni, Hor, Pooja, Ichida, Justin K.
Publicado no Brain Res (2015)

High fidelity TNA synthesis by Therminator polymerase

Por Ichida, Justin K., Horhota, Allen, Zou, Keyong, McLaughlin, Larry W., Szostak, Jack W.
Publicado em 2005

Nanog-Independent Reprogramming to iPSCs with Canonical Factors

Por Carter, Ava C., Davis-Dusenbery, Brandi N., Koszka, Kathryn, Ichida, Justin K., Eggan, Kevin
Publicado em 2014

Ketamine Exposure in Early Development Impairs Specification of the Primary Germ Cell Layers

Por Akeju, Oluwaseun, Davis-Dusenbery, Brandi N, Cassel, Seth H., Ichida, Justin K., Eggan, Kevin
Publicado em 2014

An in Vitro Selection System for TNA

Por Ichida, Justin K., Zou, Keyong, Horhota, Allen, Yu, Biao, McLaughlin, Larry W., Szostak, Jack W.
Publicado no J Am Chem Soc (2005)

Conversion of Mouse and Human Fibroblasts into Functional Spinal Motor Neurons

Por Son, Esther Y., Ichida, Justin K., Wainger, Brian J., Toma, Jeremy S., Rafuse, Victor F., Woolf, Clifford J., Eggan, Kevin
Publicado em 2011

Kinetic Analysis of an Efficient DNA-Dependent TNA Polymerase

Por Horhota, Allen, Zou, Keyong, Ichida, Justin K., Yu, Biao, McLaughlin, Larry W., Szostak, Jack W., Chaput, John C.
Publicado no J Am Chem Soc (2005)

Derivation of Induced Pluripotent Stem Cells from the Baboon: A Nonhuman Primate Model for Preclinical Testing of Stem Cell Therapies

Por Navara, Christopher S., Hornecker, Jacey, Grow, Douglas, Chaudhari, Shital, Hornsby, Peter J., Ichida, Justin K., Eggan, Kevin, McCarrey, John R.
Publicado em 2013

Effect of Stalling after Mismatches on the Error Catastrophe in Nonenzymatic Nucleic Acid Replication

Por Rajamani, Sudha, Ichida, Justin K., Antal, Tibor, Treco, Douglas A., Leu, Kevin, Nowak, Martin A., Szostak, Jack W., Chen, Irene A.
Publicado em 2010

Motoneurons Derived from Induced Pluripotent Stem Cells Develop Mature Phenotypes Typical of Endogenous Spinal Motoneurons

Por Toma, Jeremy S., Shettar, Basavaraj C., Chipman, Peter H., Pinto, Devanand M., Borowska, Joanna P., Ichida, Justin K., Fawcett, James P., Zhang, Ying, Eggan, Kevin, Rafuse, Victor F.
Publicado no J Neurosci (2015)

β-Catenin Functions Pleiotropically in Differentiation and Tumorigenesis in Mouse Embryo-Derived Stem Cells

Por Okumura, Noriko, Akutsu, Hidenori, Sugawara, Tohru, Miura, Takumi, Takezawa, Youki, Hosoda, Akihiro, Yoshida, Keiichi, Ichida, Justin K., Yamada, Mitsutoshi, Hamatani, Toshio, Kuji, Naoaki, Miyado, Kenji, Yoshimura, Yasunori, Umezawa, Akihiro
Publicado em 2013

Antisense Proline-Arginine RAN dipeptides linked to C9ORF72-ALS/FTD form toxic nuclear aggregates that initiate in vitro and in vivo neuronal death

Por Wen, Xinmei, Tan, Wenzhi, Westergard, Thomas, Krishnamurthy, Karthik, ShamamandriMarkandaiah, Shashirekha, Shi, Yingxiao, Lin, Shaoyu, Shneider, Neil A., Monaghan, John, Pandey, Udai B., Pasinelli, Piera, Ichida, Justin K., Trotti, Davide
Publicado no Neuron (2014)

Iroquois proteins promote skeletal joint formation by maintaining chondrocytes in an immature state

Por Askary, Amjad, Mork, Lindsey, Paul, Sandeep, He, Xinjun, Izuhara, Audrey K., Gopalakrishnan, Suhasni, Ichida, Justin K., McMahon, Andrew P., Dabizljevic, Sonja, Dale, Rodney, Mariani, Francesca V., Crump, J. Gage
Publicado no Dev Cell (2015)

Reprogramming within hours following nuclear transfer into mouse but not human zygotes

Por Egli, Dieter, Chen, Alice E., Saphier, Genevieve, Ichida, Justin, Fitzgerald, Claire, Go, Kathryn J., Acevedo, Nicole, Patel, Jay, Baetscher, Manfred, Kearns, William G., Goland, Robin, Leibel, Rudolph L., Melton, Douglas A., Eggan, Kevin
Publicado em 2011

Notch inhibition allows oncogene independent generation of iPS cells

Por Ichida, Justin K., TCW, Julia, Williams, Luis A., Carter, Ava C., Shi, Yingxiao, Moura, Marcelo T., Ziller, Michael, Singh, Sean, Amabile, Giovanni, Bock, Christoph, Umezawa, Akihiro, Rubin, Lee L., Bradner, James E., Akutsu, Hidenori, Meissner, Alexander, Eggan, Kevin
Publicado no Nat Chem Biol (2014)

A Small Molecule Inhibitor of Tgf-β Signaling Replaces Sox2 in Reprogramming by Inducing Nanog

Por Ichida, Justin K., Blanchard, Joel, Lam, Kelvin, Son, Esther Y., Chung, Julia E., Egli, Dieter, Loh, Kyle M., Carter, Ava C., Di Giorgio, Francesco P., Koszka, Kathryn, Huangfu, Danwei, Akutsu, Hidenori, Liu, David R., Rubin, Lee L., Eggan, Kevin
Publicado em 2009

Modeling pain in vitro using nociceptor neurons reprogrammed from fibroblasts

Por Wainger, Brian J., Buttermore, Elizabeth D., Oliveira, Julia T., Mellin, Cassidy, Lee, Seungkyu, Saber, Wardiya Afshar, Wang, Amy, Ichida, Justin K., Chiu, Isaac M., Barrett, Lee, Huebner, Eric A., Bilgin, Canan, Tsujimoto, Naomi, Brenneis, Christian, Kapur, Kush, Rubin, Lee L., Eggan, Kevin, Woolf, Clifford J.
Publicado no Nat Neurosci (2014)

The RNA kinase CLP1 links tRNA metabolism to progressive motor neuron loss

Por Hanada, Toshikatsu, Weitzer, Stefan, Mair, Barbara, Bernreuther, Christian, Wainger, Brian J., Ichida, Justin, Hanada, Reiko, Orthofer, Michael, Cronin, Shane J, Komnenovic, Vukislav, Minis, Adi, Sato, Fuminori, Mimata, Hiromitsu, Yoshimura, Akihiko, Tamir, Ido, Rainer, Johannes, Kofler, Reinhard, Yaron, Avraham, Eggan, Kevin C., Woolf, Clifford J., Glatzel, Markus, Herbst, Ruth, Martinez, Javier, Penninger, Josef M.
Publicado em 2013

Central role for PICALM in amyloid–β blood–brain barrier transcytosis and clearance

Por Zhao, Zhen, Sagare, Abhay P., Ma, Qingyi, Halliday, Matthew R., Kong, Pan, Kisler, Kassandra, Winkler, Ethan A., Ramanathan, Anita, Kanekiyo, Takahisa, Bu, Guojun, Owens, Nelly Chuqui, Rege, Sanket V., Si, Gabriel, Ahuja, Ashim, Zhu, Donghui, Miller, Carol A., Schneider, Julie A., Maeda, Manami, Maeda, Takahiro, Sugawara, Tohru, Ichida, Justin K., Zlokovic, Berislav V.
Publicado no Nat Neurosci (2015)