Reprogramming within hours following nuclear transfer into mouse but not human zygotes

Fertilized mouse zygotes can reprogram somatic cells to a pluripotent state. Human zygotes might therefore be useful for producing patient-derived pluripotent stem cells. However, logistical, legal and social considerations have limited the availability of human eggs for research. Here we show that...

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Hlavní autoři: Egli, Dieter, Chen, Alice E., Saphier, Genevieve, Ichida, Justin, Fitzgerald, Claire, Go, Kathryn J., Acevedo, Nicole, Patel, Jay, Baetscher, Manfred, Kearns, William G., Goland, Robin, Leibel, Rudolph L., Melton, Douglas A., Eggan, Kevin
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335196/
https://ncbi.nlm.nih.gov/pubmed/21971503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1503
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