Reprogramming within hours following nuclear transfer into mouse but not human zygotes

Fertilized mouse zygotes can reprogram somatic cells to a pluripotent state. Human zygotes might therefore be useful for producing patient-derived pluripotent stem cells. However, logistical, legal and social considerations have limited the availability of human eggs for research. Here we show that...

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Detalhes bibliográficos
Main Authors: Egli, Dieter, Chen, Alice E., Saphier, Genevieve, Ichida, Justin, Fitzgerald, Claire, Go, Kathryn J., Acevedo, Nicole, Patel, Jay, Baetscher, Manfred, Kearns, William G., Goland, Robin, Leibel, Rudolph L., Melton, Douglas A., Eggan, Kevin
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335196/
https://ncbi.nlm.nih.gov/pubmed/21971503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1503
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