A Small Molecule Inhibitor of Tgf-β Signaling Replaces Sox2 in Reprogramming by Inducing Nanog

The combined activity of three transcription factors can reprogram adult cells into induced pluripotent stem (iPS) cells. However, the transgenic methods used to deliver reprogramming factors have raised concerns regarding the future utility of the resulting stem cells. These uncertainties could be...

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Autores principales: Ichida, Justin K., Blanchard, Joel, Lam, Kelvin, Son, Esther Y., Chung, Julia E., Egli, Dieter, Loh, Kyle M., Carter, Ava C., Di Giorgio, Francesco P., Koszka, Kathryn, Huangfu, Danwei, Akutsu, Hidenori, Liu, David R., Rubin, Lee L., Eggan, Kevin
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335195/
https://ncbi.nlm.nih.gov/pubmed/19818703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2009.09.012
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