Motoneurons Derived from Induced Pluripotent Stem Cells Develop Mature Phenotypes Typical of Endogenous Spinal Motoneurons

Induced pluripotent cell-derived motoneurons (iPSCMNs) are sought for use in cell replacement therapies and treatment strategies for motoneuron diseases such as amyotrophic lateral sclerosis (ALS). However, much remains unknown about the physiological properties of iPSCMNs and how they compare with...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Toma, Jeremy S., Shettar, Basavaraj C., Chipman, Peter H., Pinto, Devanand M., Borowska, Joanna P., Ichida, Justin K., Fawcett, James P., Zhang, Ying, Eggan, Kevin, Rafuse, Victor F.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4402330/
https://ncbi.nlm.nih.gov/pubmed/25609642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2126-14.2015
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