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Direct optical activation of skeletal muscle fibres efficiently controls muscle contraction and attenuates denervation atrophy

Neural prostheses can restore meaningful function to paralysed muscles by electrically stimulating innervating motor axons, but fail when muscles are completely denervated, as seen in amyotrophic lateral sclerosis, or after a peripheral nerve or spinal cord injury. Here we show that channelrhodopsin...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Magown, Philippe, Shettar, Basavaraj, Zhang, Ying, Rafuse, Victor F.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4633712/
https://ncbi.nlm.nih.gov/pubmed/26460719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9506
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