Genetic variation in human DNA replication timing

por Koren, Amnon, Handsaker, Robert E., Kamitaki, Nolan, Karlić, Rosa, Ghosh, Sulagna, Polak, Paz, Eggan, Kevin, McCarroll, Steven A.
Publicado no Cell (2014)

Convergence of independent DISC1 mutations on impaired neurite growth via decreased UNC5D expression

por Srikanth, Priya, Lagomarsino, Valentina N., Pearse, Richard V., Liao, Meichen, Ghosh, Sulagna, Nehme, Ralda, Seyfried, Nicholas, Eggan, Kevin, Young-Pearse, Tracy L.
Publicado no Transl Psychiatry (2018)

The C9orf72-interacting protein Smcr8 is a negative regulator of autoimmunity and lysosomal exocytosis

por Zhang, Yingying, Burberry, Aaron, Wang, Jin-Yuan, Sandoe, Jackson, Ghosh, Sulagna, Udeshi, Namrata D., Svinkina, Tanya, Mordes, Daniel A., Mok, Joanie, Charlton, Maura, Li, Quan-Zhen, Carr, Steven A., Eggan, Kevin
Publicado no Genes Dev (2018)

Oligodendrocyte differentiation of induced pluripotent stem cells derived from subjects with schizophrenias implicate abnormalities in development

por McPhie, Donna L., Nehme, Ralda, Ravichandran, Caitlin, Babb, Suzann M., Ghosh, Sulagna Dia, Staskus, Alexandra, Kalinowski, Amy, Kaur, Rupinderjit, Douvaras, Panagiotis, Du, Fei, Ongur, Dost, Fossati, Valentina, Eggan, Kevin, Cohen, Bruce M.
Publicado no Transl Psychiatry (2018)

Publicly Available hiPSC Lines with Extreme Polygenic Risk Scores for Modeling Schizophrenia

por Dobrindt, Kristina, Zhang, Hanwen, Das, Debamitra, Abdollahi, Sara, Prorok, Tim, Ghosh, Sulagna, Weintraub, Sarah, Genovese, Giulio, Powell, Samuel K., Lund, Anina, Akbarian, Schahram, Eggan, Kevin, McCarroll, Steven, Duan, Jubao, Avramopoulos, Dimitrios, Brennand, Kristen J.
Publicado no Complex Psychiatry (2021)

Human pluripotent stem cells recurrently acquire and expand dominant negative P53 mutations

por Merkle, Florian T., Ghosh, Sulagna, Kamitaki, Nolan, Mitchell, Jana, Avior, Yishai, Mello, Curtis, Kashin, Seva, Mekhoubad, Shila, Ilic, Dusko, Charlton, Maura, Saphier, Genevieve, Handsaker, Robert E., Genovese, Giulio, Bar, Shiran, Benvenisty, Nissim, McCarroll, Steven A., Eggan, Kevin
Publicado no Nature (2017)

Loss-of-function mutations in the C9ORF72 mouse ortholog cause fatal autoimmune disease()

por Burberry, Aaron, Suzuki, Naoki, Wang, Jin-Yuan, Moccia, Rob, Mordes, Daniel A., Stewart, Morag, Suzuki-Uematsu, Satomi, Ghosh, Sulagna, Singh, Ajay, Merkle, Florian T., Koszka, Kathryn, Li, Quan-Zhen, Zon, Leonard, Rossi, Derrick J., Trowbridge, Jennifer J., Notarangelo, Luigi D., Eggan, Kevin
Publicado no Sci Transl Med (2016)

Combining NGN2 Programming with Developmental Patterning Generates Human Excitatory Neurons with NMDAR-Mediated Synaptic Transmission

por Nehme, Ralda, Zuccaro, Emanuela, Dia Ghosh, Sulagna, Li, Chenchen, Sherwood, John L., Pietilainen, Olli, Barrett, Lindy E., Limone, Francesco, Worringer, Kathleen A., Kommineni, Sravya, Zang, Ying, Cacchiarelli, Davide, Meissner, Alex, Adolfsson, Rolf, Haggarty, Stephen, Madison, Jon, Muller, Matthias, Arlotta, Paola, Fu, Zhanyan, Feng, Guoping, Eggan, Kevin
Publicado no Cell Rep (2018)

Dysregulated protocadherin-pathway activity as an intrinsic defect in iPSC-derived cortical interneurons from patients with schizophrenia

por Shao, Zhicheng, Noh, Haneul, Kim, Woong Bin, Ni, Peiyan, Nguyen, Christine, Cote, Sarah E., Noyes, Elizabeth, Zhao, Joyce, Parsons, Teagan, Park, James M., Zheng, Kelvin, Park, Joshua J., Coyle, Joseph T., Weinberger, Daniel R., Straub, Richard E., Berman, Karen F., Apud, Jose, Ongur, Dost, Cohen, Bruce M., McPhie, Donna L., Rapoport, Judith L., Perlis, Roy H., Lanz, Thomas A., Xi, Hualin Simon, Yin, Changhong, Huang, Weihua, Hirayama, Teruyoshi, Fukuda, Emi, Yagi, Takeshi, Ghosh, Sulagna, Eggan, Kevin C., Kim, Hae-Young, Eisenberg, Leonard M., Moghadam, Alexander A., Stanton, Patric K., Cho, Jun-Hyeong, Chung, Sangmi
Publicado no Nat Neurosci (2019)

Exome sequencing in amyotrophic lateral sclerosis implicates a novel gene, DNAJC7 encoding a heat-shock protein

por Farhan, Sali M.K., Howrigan, Daniel P., Abbott, Liam E., Klim, Joseph R., Topp, Simon D., Byrnes, Andrea E., Churchhouse, Claire, Phatnani, Hemali, Smith, Bradley N., Rampersaud, Evadnie, Wu, Gang, Wuu, Joanne, Shatunov, Aleksey, Iacoangeli, Alfredo, Khleifat, Ahmad Al, Mordes, Daniel A., Ghosh, Sulagna, Eggan, Kevin, Rademakers, Rosa, McCauley, Jacob L., Schüle, Rebecca, Züchner, Stephan, Benatar, Michael, Taylor, J. Paul, Nalls, Michael, Gotkine, Marc, Shaw, Pamela J., Morrison, Karen E., Al-Chalabi, Ammar, Traynor, Bryan, Shaw, Christopher E., Goldstein, David B., Harms, Matthew B., Daly, Mark J., Neale, Benjamin M.
Publicado no Nat Neurosci (2019)