Publicly Available hiPSC Lines with Extreme Polygenic Risk Scores for Modeling Schizophrenia

Schizophrenia (SZ) is a common and debilitating psychiatric disorder with limited effective treatment options. Although highly heritable, risk for this polygenic disorder depends on the complex interplay of hundreds of common and rare variants. Translating the growing list of genetic loci significan...

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Detalhes bibliográficos
Publicado no:Complex Psychiatry
Main Authors: Dobrindt, Kristina, Zhang, Hanwen, Das, Debamitra, Abdollahi, Sara, Prorok, Tim, Ghosh, Sulagna, Weintraub, Sarah, Genovese, Giulio, Powell, Samuel K., Lund, Anina, Akbarian, Schahram, Eggan, Kevin, McCarroll, Steven, Duan, Jubao, Avramopoulos, Dimitrios, Brennand, Kristen J.
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7923934/
https://ncbi.nlm.nih.gov/pubmed/34883504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000512716
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