The C9orf72-interacting protein Smcr8 is a negative regulator of autoimmunity and lysosomal exocytosis

While a mutation in C9ORF72 is the most common genetic contributor to amyotrophic lateral sclerosis (ALS), much remains to be learned concerning the function of the protein normally encoded at this locus. To elaborate further on functions for C9ORF72, we used quantitative mass spectrometry-based pro...

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Bibliografiska uppgifter
I publikationen:Genes Dev
Huvudupphovsmän: Zhang, Yingying, Burberry, Aaron, Wang, Jin-Yuan, Sandoe, Jackson, Ghosh, Sulagna, Udeshi, Namrata D., Svinkina, Tanya, Mordes, Daniel A., Mok, Joanie, Charlton, Maura, Li, Quan-Zhen, Carr, Steven A., Eggan, Kevin
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cold Spring Harbor Laboratory Press 2018
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6075033/
https://ncbi.nlm.nih.gov/pubmed/29950492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.313932.118
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