The C9orf72-interacting protein Smcr8 is a negative regulator of autoimmunity and lysosomal exocytosis

While a mutation in C9ORF72 is the most common genetic contributor to amyotrophic lateral sclerosis (ALS), much remains to be learned concerning the function of the protein normally encoded at this locus. To elaborate further on functions for C9ORF72, we used quantitative mass spectrometry-based pro...

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Bibliographische Detailangaben
Veröffentlicht in:Genes Dev
Hauptverfasser: Zhang, Yingying, Burberry, Aaron, Wang, Jin-Yuan, Sandoe, Jackson, Ghosh, Sulagna, Udeshi, Namrata D., Svinkina, Tanya, Mordes, Daniel A., Mok, Joanie, Charlton, Maura, Li, Quan-Zhen, Carr, Steven A., Eggan, Kevin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2018
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6075033/
https://ncbi.nlm.nih.gov/pubmed/29950492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.313932.118
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