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The C9orf72-SMCR8-WDR41 complex is a GAP for small GTPases

Massive expansions of the hexanucleotide in C9orf72 are the primary genetic origins of familial amyotrophic lateral sclerosis (ALS) and frontal temporal dementia (FTD). Current studies have found that this repeat sequence participates in the disease process by producing neurotoxic substances and red...

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Bibliografische gegevens
Gepubliceerd in:Autophagy
Hoofdauteurs: Tang, Dan, Sheng, Jingwen, Xu, Liangting, Yan, Chuangye, Qi, Shiqian
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7469575/
https://ncbi.nlm.nih.gov/pubmed/32521185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2020.1779473
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