The C9orf72-SMCR8-WDR41 complex is a GAP for small GTPases

Massive expansions of the hexanucleotide in C9orf72 are the primary genetic origins of familial amyotrophic lateral sclerosis (ALS) and frontal temporal dementia (FTD). Current studies have found that this repeat sequence participates in the disease process by producing neurotoxic substances and red...

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Foilsithe in:Autophagy
Main Authors: Tang, Dan, Sheng, Jingwen, Xu, Liangting, Yan, Chuangye, Qi, Shiqian
Formáid: Artigo
Teanga:Inglês
Foilsithe: Taylor & Francis 2020
Ábhair:
Autophagic Punctum
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7469575/
https://ncbi.nlm.nih.gov/pubmed/32521185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2020.1779473
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