The C9orf72-SMCR8-WDR41 complex is a GAP for small GTPases

Massive expansions of the hexanucleotide in C9orf72 are the primary genetic origins of familial amyotrophic lateral sclerosis (ALS) and frontal temporal dementia (FTD). Current studies have found that this repeat sequence participates in the disease process by producing neurotoxic substances and red...

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Detalles Bibliográficos
Publicado en:Autophagy
Autores principales: Tang, Dan, Sheng, Jingwen, Xu, Liangting, Yan, Chuangye, Qi, Shiqian
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2020
Materias:
Autophagic Punctum
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7469575/
https://ncbi.nlm.nih.gov/pubmed/32521185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2020.1779473
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