The DNA damage response in immunotherapy and radiation

by Samstein, Robert M., Riaz, Nadeem
Published in Adv Radiat Oncol (2018)

Dissecting microsatellite instability in colorectal cancer: one size does not fit all

by Samstein, Robert M., Chan, Timothy A.
Published in Genome Med (2017)

Advancing scientific knowledge in times of pandemics

by Vabret, Nicolas, Samstein, Robert, Fernandez, Nicolas, Merad, Miriam
Published in Nat Rev Immunol (2020)

Locally Advanced and Unresectable Cutaneous Squamous Cell Carcinoma: Outcomes of Concurrent Cetuximab and Radiotherapy

by Samstein, Robert M., Ho, Alan L., Lee, Nancy Y., Barker, Christopher A.
Published 2014

Tumor mutational burden as a predictive biomarker for checkpoint inhibitor immunotherapy

by Lee, Mark, Samstein, Robert M., Valero, Cristina, Chan, Timothy A., Morris, Luc G.T.
Published in Hum Vaccin Immunother (2019)

Extrathymic generation of regulatory T cells in placental mammals mitigates maternal-fetal conflict

by Samstein, Robert M., Josefowicz, Steven Z., Arvey, Aaron, Treuting, Piper M., Rudensky, Alexander Y.
Published 2012

CD4(+) regulatory T cells control Th17 responses in a Stat3-dependent manner

by Chaudhry, Ashutosh, Rudra, Dipayan, Treuting, Piper, Samstein, Robert M., Liang, Yuqiong, Kas, Arnold, Rudensky, Alexander Y.
Published in Science (2009)

Inflammation-induced repression of Foxp3-bound chromatin in regulatory T cells

by Arvey, Aaron, van der Veeken, Joris, Samstein, Robert M., Feng, Yongqiang, Stamatoyannopoulos, John A., Rudensky, Alexander Y.
Published 2014

DNA Repair Gene Mutations as Predictors of Immune Checkpoint Inhibitor Response beyond Tumor Mutation Burden

by Hsiehchen, David, Hsieh, Antony, Samstein, Robert M., Lu, Tianshi, Beg, Muhammad S., Gerber, David E., Wang, Tao, Morris, Luc G.T., Zhu, Hao
Published in Cell Rep Med (2020)

Localized Sinonasal Mucosal Melanoma: Outcomes and Associations with Stage, Radiotherapy and PET Response

by Samstein, Robert M., Carvajal, Richard D., Postow, Michael A., Callahan, Margaret K., Shoushtari, Alexander N., Patel, Snehal G., Lee, Nancy Y., Barker, Christopher A.
Published in Head Neck (2016)

Transcription factor Foxp3 and its protein partners form a complex regulatory network

by Rudra, Dipayan, deRoos, Paul, Chaudhry, Ashutosh, Niec, Rachel, Arvey, Aaron, Samstein, Robert M., Leslie, Christina, Shaffer, Scott A., Goodlett, David R., Rudensky, Alexander Y.
Published 2012

Interleukin-10 signaling in regulatory T cells is required for suppression of Th17 cell-mediated inflammation

by Chaudhry, Ashutosh, Samstein, Robert M., Treuting, Piper, Liang, Yuqiong, Pils, Marina C., Heinrich, Jan-Michael, Jack, Robert S., Wunderlich, F. Thomas, Brüning, Jens C., Müller, Werner, Rudensky, Alexander Y.
Published 2011

Shared immunogenic poly-epitope frameshift mutations in microsatellite unstable tumors

by Roudko, Vladimir, Bozkus, Cansu Cimen, Orfanelli, Theofano, McClain, Christopher B., Carr, Caitlin, O’Donnell, Timothy, Chakraborty, Lauren, Samstein, Robert, Huang, Kuan-lin, Blank, Stephanie V., Greenbaum, Benjamin, Bhardwaj, Nina
Published in Cell (2020)

Safety of combining thoracic radiation therapy with concurrent versus sequential immune checkpoint inhibition

by von Reibnitz, Donata, Chaft, Jamie E., Wu, Abraham J., Samstein, Robert, Hellmann, Matthew D., Plodkowski, Andrew J., Zhang, Zhigang, Shi, Weiji, Dick-Godfrey, Rosalind, Panchoo, Kelly H., Barker, Christopher A., Rimner, Andreas
Published in Adv Radiat Oncol (2018)

Foxp3 exploits a preexistent enhancer landscape for regulatory T cell lineage specification

by Samstein, Robert M., Arvey, Aaron, Josefowicz, Steven Z., Peng, Xiao, Reynolds, Alex, Sandstrom, Richard, Neph, Shane, Sabo, Peter, Kim, Jeong M., Liao, Will, O. Li, Ming, Leslie, Christina, Stamatoyannopoulos, John A., Rudensky, Alexander Y.
Published 2012

Genomic Analyses for Predictors of Response to Chemoradiation in Stage III Non-Small Cell Lung Cancer

by Luo, Leo Y., Samstein, Robert M., Dick-Godfrey, Rosalind, Sidiqi, Baho, Wang, Chunyu, Oro, Federica, Sonnick, Mark, Paik, Paul K., Chaft, Jamie E., Shaverdian, Narek, Gomez, Daniel R., Rimner, Andreas, Wu, Abraham J.
Published in Adv Radiat Oncol (2020)

AN ANTI-TUMOR IMMUNE RESPONSE IS EVOKED BY PARTIAL-VOLUME SINGLE DOSE RADIATION IN TWO MURINE MODELS

by Markovsky, Ela, Budhu, Sadna, Samstein, Robert M., Li, Hongyan, Russell, James, Zhang, Zhigang, Drill, Esther, Bodden, Chloe, Chen, Qing, Powell, Simon N., Merghoub, Taha, Wolchok, Jedd D., Humm, John, Deasy, Joseph O., Haimovitz-Friedman, Adriana
Published in Int J Radiat Oncol Biol Phys (2018)

Luteinizing Hormone-Releasing Hormone Enhances T Cell Recovery following Allogeneic Bone Marrow Transplantation

by Goldberg, Gabrielle L., King, Christopher G., Nejat, Rebecca A., Suh, David Y., Smith, Odette M., Bretz, Jamison C., Samstein, Robert M., Dudakov, Jarrod A., Chidgey, Ann P., Chen-Kiang, Selina, Boyd, Richard L., van den Brink, Marcel R. M.
Published 2009

Patient HLA class I genotype influences cancer response to checkpoint blockade immunotherapy

by Chowell, Diego, Morris, Luc G. T., Grigg, Claud M., Weber, Jeffrey K., Samstein, Robert M., Makarov, Vladimir, Kuo, Fengshen, Kendall, Sviatoslav M., Requena, David, Riaz, Nadeem, Greenbaum, Benjamin, Carroll, James, Garon, Edward, Hyman, David M., Zehir, Ahmet, Solit, David, Berger, Michael, Zhou, Ruhong, Rizvi, Naiyer A., Chan, Timothy A.
Published in Science (2017)

In situ vaccination with defined factors overcomes T cell exhaustion in distant tumors

by Khalil, Danny N., Suek, Nathan, Campesato, Luis Felipe, Budhu, Sadna, Redmond, David, Samstein, Robert M., Krishna, Chirag, Panageas, Katherine S., Capanu, Marinela, Houghton, Sean, Hirschhorn, Daniel, Zappasodi, Roberta, Giese, Rachel, Gasmi, Billel, Schneider, Michael, Gupta, Aditi, Harding, James J., Moral, John Alec, Balachandran, Vinod P., Wolchok, Jedd D., Merghoub, Taha
Published in J Clin Invest (2019)