Interleukin-10 signaling in regulatory T cells is required for suppression of Th17 cell-mediated inflammation

Effector CD4(+) T cell subsets, whose differentiation is facilitated by distinct cytokine cues, amplify the corresponding type of inflammatory response. Regulatory T (Treg) cells integrate environmental cues to suppress particular types of inflammation. In this regard, STAT3, a transcription factor...

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Detalhes bibliográficos
Main Authors: Chaudhry, Ashutosh, Samstein, Robert M., Treuting, Piper, Liang, Yuqiong, Pils, Marina C., Heinrich, Jan-Michael, Jack, Robert S., Wunderlich, F. Thomas, Brüning, Jens C., Müller, Werner, Rudensky, Alexander Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088485/
https://ncbi.nlm.nih.gov/pubmed/21511185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2011.03.018
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