Th17 cells express interleukin-10 receptor and are controlled by Foxp3(−) and Foxp3(+) regulatory CD4(+) T cells in an interleukin-10 dependent manner

T helper 17 (Th17) cells are important for host defense against extra-cellular microorganisms. However they are also implicated in autoimmune and chronic inflammatory diseases, and as such need to be tightly regulated. The mechanisms that directly control committed pathogenic Th17 cells in vivo rema...

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Hauptverfasser: Huber, Samuel, Gagliani, Nicola, Esplugues, Enric, O’Connor, William, Huber, Francis J., Chaudhry, Ashutosh, Kamanaka, Masahito, Kobayashi, Yasushi, Booth, Carmen J., Rudensky, Alexander Y., Battaglia, Manuela, Roncarolo, Maria Grazia, Flavell, Richard A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3113617/
https://ncbi.nlm.nih.gov/pubmed/21511184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2011.01.020
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