Conventional T-bet(+)Foxp3(−) Th1 cells are the major source of host-protective regulatory IL-10 during intracellular protozoan infection

Although interferon γ (IFN-γ) secretion is essential for control of most intracellular pathogens, host survival often also depends on the expression of interleukin 10 (IL-10), a cytokine known to counteract IFN-γ effector functions. We analyzed the source of regulatory IL-10 in mice infected with th...

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Hlavní autoři: Jankovic, Dragana, Kullberg, Marika C., Feng, Carl G., Goldszmid, Romina S., Collazo, Carmen M., Wilson, Mark, Wynn, Thomas A., Kamanaka, Masahito, Flavell, Richard A., Sher, Alan
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2007
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118735/
https://ncbi.nlm.nih.gov/pubmed/17283209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20062175
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