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TAP-1 indirectly regulates CD4(+) T cell priming in Toxoplasma gondii infection by controlling NK cell IFN-γ production
To investigate if transporter associated with antigen processing (TAP)–1 is required for CD8(+) T cell–mediated control of Toxoplasma gondii in vivo, we compared the resistance of TAP-1(−/−), CD8(−/−), and wild-type (WT) mice to infection with the parasite. Unexpectedly, TAP-1(−/−) mice displayed gr...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2118487/ https://ncbi.nlm.nih.gov/pubmed/17923502 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20070634 |
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