TAP-1 indirectly regulates CD4(+) T cell priming in Toxoplasma gondii infection by controlling NK cell IFN-γ production

To investigate if transporter associated with antigen processing (TAP)–1 is required for CD8(+) T cell–mediated control of Toxoplasma gondii in vivo, we compared the resistance of TAP-1(−/−), CD8(−/−), and wild-type (WT) mice to infection with the parasite. Unexpectedly, TAP-1(−/−) mice displayed gr...

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Bibliografske podrobnosti
Main Authors: Goldszmid, Romina S., Bafica, Andre, Jankovic, Dragana, Feng, Carl G., Caspar, Pat, Winkler-Pickett, Robin, Trinchieri, Giorgio, Sher, Alan
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2007
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118487/
https://ncbi.nlm.nih.gov/pubmed/17923502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20070634
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