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NK cell-derived interferon-γ orchestrates the cellular dynamics and differentiation of monocytes into inflammatory dendritic cells at the site of infection

Dendritic cells (DCs), monocyte and/or macrophages initiate host-protective immune responses to intracellular pathogens in part through interleukin-12 (IL-12) production, although the relative contribution of tissue resident versus recruited cells has been unclear. Here we showed that after intraper...

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Bibliographic Details
Main Authors: Goldszmid, Romina S., Caspar, Pat, Rivollier, Aymeric, White, Sandy, Dzutsev, Amiran, Hieny, Sara, Kelsall, Brian, Trinchieri, Giorgio, Sher, Alan
Format: Artigo
Language:Inglês
Published: 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412151/
https://ncbi.nlm.nih.gov/pubmed/22749354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2012.03.026
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