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Host ER–parasitophorous vacuole interaction provides a route of entry for antigen cross-presentation in Toxoplasma gondii–infected dendritic cells

Toxoplasma gondii tachyzoites infect host cells by an active invasion process leading to the formation of a specialized compartment, the parasitophorous vacuole (PV). PVs resist fusion with host cell endosomes and lysosomes and are thus distinct from phagosomes. Because the parasite remains sequeste...

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Autori principali: Goldszmid, Romina S., Coppens, Isabelle, Lev, Avital, Caspar, Pat, Mellman, Ira, Sher, Alan
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646567/
https://ncbi.nlm.nih.gov/pubmed/19153244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20082108
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